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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

SO505

Impulsivity and retention in medication-assisted treatment for opioid use disorder: do age and sex modify the association?

IMPULSIVITY AND RETENTION IN MEDICATION-ASSISTED TREATMENT FOR OPIOID USE DISORDER: DO AGE AND SEX MODIFY THE RELATIONSHIP?

The association between impulsivity and one-year retention in medication-assisted treatment varies by age, with higher impulsivity associated with lower treatment retention only among younger patients.

The study aimed to examine the association between impulsive behavior and one-year retention in medication-assisted treatment (MAT) for opioid use disorder. It used prospective cohort data from 172 patients receiving MAT at 54 community-based centers in Ontario, Canada. Impulsivity was assessed at baseline using the Short UPPS-P Impulsive Behavior Scale, and treatment status was assessed at baseline and at 3, 6, 9, and 12 months. Effect modification by age and sex was tested using multivariable logistic regression adjusted for potential confounders. The mean age of the sample was 37 years, and 50.6% were women. Higher impulsivity was associated with lower odds of one-year treatment retention among patients aged 37 years or younger (OR = 0.91; 95% confidence interval, 0.84 to 0.99), but this association weakened with increasing age and was not observed among those older than 37 years (OR = 1.01; 95% confidence interval, 0.92 to 1.10); the p-value for effect modification by age was 0.03. No effect modification by sex was detected, and the poster also reported that the positive urgency subscale was associated with lower treatment retention at age 25. The authors suggest that considering age when assessing impulsivity and using approaches that support treatment adherence, particularly among younger patients, may improve treatment retention.

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