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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

SO367

Psychiatric hospitalizations among patients with severe schizophrenia before and during treatment in a community-based case-managed programme

PSYCHIATRIC HOSPITALIZATIONS OF PATIENTS WITH SEVERE SCHIZOPHRENIA BEFORE AND DURING TREATMENT IN A COMMUNITY-BASED AND CASE-MANAGED PROGRAMME

Treatment in a comprehensive, community-based case-managed programme substantially reduced psychiatric hospitalizations and achieved high treatment retention compared with previous standard treatment; long-acting injectable antipsychotic use was associated with these outcomes.

The aim of the study was to compare psychiatric hospitalizations among patients with severe schizophrenia during standard treatment at mental health centres and during a comprehensive, community-based case-managed programme (CMP), and to examine the role of the route of antipsychotic administration (oral or long-acting injectable, LAI). This was an observational mirror-image study comparing a ten-year follow-up period with a retrospective ten-year period before treatment; 344 patients receiving integrated pharmacological and psychosocial treatment with intensive case management were followed. Reasons for leaving the programme, psychiatric hospitalizations (including whether they were involuntary), and prescribed antipsychotic medication were recorded for the ten years before treatment and during treatment. Treatment adherence in the programme was high; by the end of ten years, only 12.2% of patients had left voluntarily, compared with 84.3% during previous standard treatment. The number of patients hospitalized and the number of hospitalizations due to exacerbations decreased substantially after programme entry (p < 0.0001), as did involuntary hospitalizations (p < 0.001); the graph in the poster showed lower rates of hospitalization, suicide attempts, and treatment discontinuation than with standard treatment (p < 0.001 for hospitalizations; p < 0.0001 for suicide attempts and treatment discontinuation). LAI antipsychotic use was associated with these outcomes (p < 0.0001). The authors report that comprehensive community-based case-managed treatment for severe schizophrenia achieves high treatment retention and substantially reduces hospitalizations, and that LAI antipsychotics are clearly associated with these outcomes.

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