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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

SO081

Mental health service use during the perimenopausal years among women with premenstrual disorders

MENTAL HEALTHCARE UTILIZATION DURING PERIMENOPAUSAL AGES AMONG WOMEN WITH PREMENSTRUAL DISORDERS

Women with premenstrual disorders use substantially more healthcare services for psychiatric reasons throughout the perimenopausal years, with age-specific rate ratios ranging from 1.1 to 3 depending on the disorder.

The study aimed to assess healthcare use for psychiatric disorders during the perimenopausal years among women with premenstrual disorders (PMD). This was a nationwide matched cohort study based on Swedish national registers, covering the period from 2001 to 2022. Data sources included the National Patient Register, primary care records, the Prescribed Drug Register, the Medical Birth Register, LISA, the Total Population Register, the Cause of Death Register, and the Multi-Generation Register. PMD was identified through an ICD-10 N94.3 diagnosis and prescriptions indicated for PMD (ATC: N06AB, N06AX, N06AA, G03A, G02B); each PMD case was matched at a 1:10 ratio by birth year and region of residence. The sample comprised 62,977 women with PMD (mean age 40.3 years; SD 5.5) and 613,677 matched unexposed women. Follow-up began on the latest of the matching date, the date of turning 40, or January 1, 2001, and ended on the earliest of turning 65, death, emigration, surgical menopause, or December 31, 2022. The outcome was primary and secondary care visits with a psychiatric disorder as the primary diagnosis (ICD-10 F10–F99). Rate ratios (RRs) were calculated using Poisson regression adjusted for sociodemographic factors, parity, and somatic comorbidity. Mental health service use was higher among women with PMD; between ages 40 and 65, age-specific RRs ranged from 1.1 to 3 depending on the disorder. Service use for depression and neurotic disorders increased with age, particularly at the oldest ages, whereas use for anxiety and bipolar disorder decreased with age. Service use for psychosis and stress-related disorders peaked between approximately ages 50 and 60 and then declined. The authors conclude that a history of PMD should be considered an indicator of increased psychiatric vulnerability during the hormonal transition in midlife.

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