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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

Severe and enduring or treatment-resistant? Results of a multicenter Italian study on the longitudinal course of eating disorders

Severe enduring or treatment resistant? results from a multicenter italian study on longitudinal outcomes of eating disorders

A history of traumatic experiences and comorbidity were associated with a severe and enduring course, whereas the severity of eating disorder psychopathology was associated with treatment resistance, independently of illness duration.

The study was conducted to distinguish chronicity from treatment nonresponse in eating disorders and to identify risk factors for treatment nonresponse; the concept of severe and enduring eating disorders refers to patients with longstanding illness, whereas treatment resistance refers to low response rates across treatment attempts. A large cohort of patients diagnosed with anorexia nervosa and bulimia nervosa was enrolled in this multicenter longitudinal study, which involved all major specialized eating disorder centers in Italy. Patients with longstanding eating disorders were assessed, clinical data from their initial presentation were collected, and the same cohort was reassessed at follow-up. A history of traumatic experiences and the presence of comorbidity were associated with a severe and enduring course, whereas the severity of eating disorder psychopathology was associated with treatment resistance, independently of illness duration. The results are discussed in light of the clinical utility of distinguishing severe and enduring illness from treatment resistance and the implications for precision psychiatry.

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