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Bu sayfa, 26. Dünya Psikiyatri Kongresi'nde sunulan çalışmanın yapay zekâ desteğiyle hazırlanmış Türkçe özetidir. Çalışmanın sahibi sunan yazarlardır; atıf için orijinal kaynağa başvurun.

The association between negative symptoms of schizophrenia in adulthood and autistic symptoms in childhood

Covariation between negative symptoms of schizophrenia in adulthood and autistic symptoms in childhood

The study investigates whether childhood autistic symptoms are associated with the severity of primary negative symptoms in adults diagnosed with schizophrenia; results have not yet been reported.

Autism spectrum disorder (ASD) and schizophrenia (SCZ) are heterogeneous disorders that overlap substantially in symptom presentation but differ in their typical age of onset and in the positive symptoms of schizophrenia, such as hallucinations and delusions. Impairments in neurocognitive and social cognitive functioning arising from subtle disturbances in neural network development may place some children on a trajectory of increasing academic difficulties, social withdrawal, and isolation; these early developmental features are often reinterpreted in adulthood as primary negative symptoms (PNS). The abstract states that young people with ASD are three to six times more likely to develop schizophrenia than their neurotypical peers, and that some individuals who later develop schizophrenia exhibit functional impairments in childhood that overlap with autistic symptoms. The study therefore focuses on the relationship between childhood autistic symptoms and the severity of negative symptoms in adulthood among adults diagnosed with schizophrenia. Methodologically, adult patients diagnosed with schizophrenia attending a secondary-care psychiatric outpatient clinic in Sweden are undergoing comprehensive assessment using widely used self-report and clinician-administered assessment instruments, together with a review of clinical records. Participant recruitment, data collection, and preliminary analyses are ongoing, and preliminary findings will be presented at the conference; according to the authors, the substantial phenotypic overlap between autistic traits and primary negative symptoms may have contributed to diagnostic misclassification in individuals diagnosed with schizophrenia in adulthood.

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