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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

Introduction to OCD-Related Networks, Pathways, and Focal Interventions

Introduction to networks, tracts related to ocd and focal interventions

Although ablative interventions produce substantial symptom reduction in an average of approximately 60% of patients with severe, treatment-resistant OCD, the existence of a subgroup of nonresponders calls for a more detailed understanding to guide target selection.

The talk addresses ablative interventions that have been used for decades in psychiatric disorders, including OCD. Research over the past 20 to 30 years provides substantial support for the use of ablative interventions in severe, treatment-resistant OCD, showing significant reductions in OCD symptoms in an average of approximately 60% of patients. Nevertheless, a subgroup shows no improvement even after invasive interventions. The talk emphasizes that the cortico-striato-thalamo-striatal circuit is clearly important in the invasive treatment of OCD through stimulation or ablation, but that the considerable variability among participants necessitates a more detailed understanding of potential targets. Despite lacking today's imaging capabilities, early targeting techniques sought to focus on network pathways thought to be associated with clinical symptoms. The talk provides a brief overview of historical targeting approaches, particularly in OCD, and discusses current methods and future directions.

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