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EV1332

Suicidal behavior in patients with bipolar disorder and their first-degree relatives

SUICIDAL BEHAVIOR IN BIPOLAR DISEASE PATIENTS AND THEIR DIRECT RELATIVES

Suicidal behavior was identified in one-third of patients with bipolar disorder presenting to the emergency department, and the vast majority of these patients had a first-degree relative who had attempted suicide.

The aim of the study was to examine the occurrence of suicidal behavior in adult patients with bipolar disorder seen in emergency departments and in their first-degree relatives. This descriptive prospective study was conducted over the three-year period from 2022 to 2024. Data were collected through interviews, reviews of clinical records, reports from relatives, and psychological autopsy techniques for suicidal behavior. A total of 3,480 patients (aged 18 to 64 years) were assessed; 378 (10.9%) had bipolar disorder, and suicidal behavior was identified in 126 (33.3%) of this group. Among those with suicidal behavior, 111 (88.1%) had a first-degree relative who had attempted suicide (12 men, 10.8%; 99 women, 89.2%), and death by suicide was reported in 11 relatives (9.9%) (6 men, 54.5%; 5 women, 45.5%). The distribution of suicide attempts by family relationship was as follows: siblings, 38.9%; parents, 34.9%; children, 16.7%; grandparents, 2.4%; and others, 7.1%. For deaths by suicide, the distribution was siblings, 45.5%; parents, 18.2%; children, 18.2%; grandparents, 15.1%; and others, 3.0%. The authors note that rates of suicidal behavior were high among patients with bipolar disorder and their first-degree relatives, that suicide attempts were concentrated among female siblings and parents, and that deaths by suicide followed a similar pattern of family relationships, with a slight male predominance. They emphasize the need to strengthen research in this area.

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