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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV1056

Suicide mortality among individuals diagnosed with borderline personality disorder: A nationwide study of the Swedish population

SUICIDE MORTALITY IN INDIVIDUALS DIAGNOSED WITH BORDERLINE PERSONALITY DISORDER: A NATIONWIDE STUDY OF THE SWEDISH POPULATION

In the Swedish population, the cumulative incidence of suicide among individuals diagnosed with borderline personality disorder was 4.9% at 20 years after the initial diagnosis, with a more than 26-fold increase in risk compared with the general population.

The aim was to determine the absolute and relative risks of suicide in borderline personality disorder (BPD) at a national level, given the wide variation in suicide risk estimates, ranging from 3% to 10%, and the lack of population-representative studies. Using the Swedish National Patient Register and Cause of Death Register, 26,716 individuals born between 1982 and 2006 who were diagnosed with BPD (ICD-10 F60.3) at age 15 or older between 1997 and 2024 were compared with 10 individuals from the general population per case, matched by sex, birth year, Swedish-born status, and region of residence using incidence density sampling. Suicide was defined using ICD-10 codes X60-84, Y87.0, Y10-34, and Y87.2; cumulative incidence was used to estimate absolute risk, and Cox regression was used to estimate relative risk. At 20 years after the initial diagnosis or the start of follow-up, the cumulative incidence of suicide was 4.9% (95% CI: 4.2–5.5) in the BPD group and 0.2% in the general population, with a hazard ratio (HR) of 26.3 (95% CI: 22.5–30.8). Poisoning was the most common method of suicide in the BPD group (45.6%). Inpatient treatment (HR: 2.7; 95% CI: 2.0–3.8) and involuntary psychiatric treatment (HR: 6.5; 95% CI: 5.2–8.2), compared with outpatient care alone, as well as psychotropic polypharmacy (HR: 1.5; 95% CI: 1.4–1.6), increased the risk. Self-harm in the year before the initial diagnosis (HR: 2.8; 95% CI: 2.4–3.3), substance use disorder (HR: 2.5; 95% CI: 2.1–2.9), and psychotic disorder (HR: 2.3; 95% CI: 1.7–3.2) were associated with risk, whereas ADHD (HR: 1.1; 95% CI: 0.9–1.4) and bipolar disorder (HR: 1.0; 95% CI: 0.8–1.3) were not. The suicide incidence rate peaks around the time of the initial diagnosis and at younger ages, and a detailed understanding of these risks is essential for individualized interventions aimed at reducing suicide.

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