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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV1018

From seizure control to loss of contact with reality: a case report of levetiracetam-induced psychiatric adverse effects

FROM SEIZURE CONTROL TO LOSS OF REALITY: A CASE REPORT OF LEVETIRACETAM-INDUCED PSYCHIATRIC SIDE EFFECTS

In a patient who developed marked behavioral changes and transient psychotic symptoms after starting levetiracetam, dose adjustment and supportive care resulted in complete recovery.

This case report aims to draw attention to the rare psychiatric adverse effects of levetiracetam, an antiepileptic drug widely used because of its efficacy and generally favorable safety profile. Mood changes, irritability, aggression, hallucinations, and, rarely, psychosis have been reported in the literature. The reported case concerns a female patient who developed marked behavioral changes and transient psychotic symptoms after starting levetiracetam. The patient's clinical history, seizure pattern, and previous treatments were reviewed; neuropsychiatric symptoms were closely monitored through regular clinical assessments and caregiver reports following treatment initiation, and relevant laboratory tests and imaging studies were performed to rule out other causes. After levetiracetam was initiated, the patient developed marked behavioral changes, irritability, and transient psychotic symptoms, including hallucinations and disorientation. The symptoms resolved following dose adjustment and supportive treatment, and no long-term neurological sequelae were observed. This case highlights the importance of close monitoring for neuropsychiatric symptoms, particularly during the early stages of treatment, to enable timely intervention and safe continuation of treatment.

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