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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV0728

Defining a Research Framework to Understand the Implementation of Pre-Exposure Prophylaxis (PrEP) for HIV Prevention in Psychiatric Care Settings

DEFINING A RESEARCH FRAMEWORK TO UNDERSTAND IMPLEMENTATION OF PRE-EXPOSURE PROPHYLAXIS (PREP) FOR HIV PREVENTION WITHIN PSYCHIATRIC CARE SETTINGS

People with mental illness remain largely excluded from the literature informing biomedical HIV prevention, and a framework comprising six interrelated research domains is proposed for integrating PrEP into psychiatric care.

The study aims to define a systematic research framework for understanding the implementation of pre-exposure prophylaxis (PrEP) for HIV prevention in psychiatric care settings. The methods involved reviewing the existing literature on HIV prevention and mental health interventions, as well as the epidemiological literature, and identifying that most existing studies targeted behavioral change rather than biomedical prevention; the framework was designed as the foundation for a research portfolio on integrated HIV and mental health care. Background data indicate that HIV incidence among people with mental illness is up to 10 times higher than in the general population, that although daily PrEP is up to 99% effective, it is prescribed to only approximately 36% of patients in the United States for whom it is indicated, and that fewer than 1% of people with bipolar disorder or schizophrenia were prescribed PrEP between 2013 and 2018. The proposed framework comprises six interrelated domains: patient perspectives, psychiatrist perspectives, missed opportunities for HIV prevention at the population level, availability of HIV prevention services, clinician-focused education and support, and ethics in HIV prevention research. These six studies were brought together within a shared evidence base and have informed various clinical initiatives integrating PrEP into psychiatric care in the United States. The authors note that psychiatric care offers a unique entry point for access to PrEP, that a multifaceted approach is needed because the literature is still emerging, and that the framework supports a transferable “no wrong door” model in psychiatric care settings.

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