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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV0579

Mindfulness and body-based interventions for opioid-related outcomes: a systematic review and meta-analysis

MINDFULNESS AND BODY BASED INTERVENTIONS FOR OPIOID RELATED OUTCOMES A SYSTEMATIC REVIEW AND META ANALYSIS

A meta-analysis pooling four controlled studies found no statistically significant benefit of mindfulness and body-based interventions for opioid craving, anxiety, pain, or depression.

The aim was to evaluate the effectiveness of mindfulness and body-based interventions, proposed as adjunctive treatments for opioid use disorder, which is characterized by high relapse rates and psychiatric comorbidity, on opioid craving, anxiety, pain, and depression. A systematic review and meta-analysis of controlled studies was conducted; studies evaluating mindfulness-oriented recovery enhancement, yoga-based therapy, and mindfulness-based addiction treatments were screened. A random-effects meta-analysis using standardized mean differences (SMDs) was performed for post-treatment outcomes, and heterogeneity was assessed using the I-squared statistic. A total of 4 studies and 544 participants were included. No statistically significant effect was found for any outcome: opioid craving, SMD = 0.43 reduction (95% confidence interval [CI], 5.24 reduction to 4.39 increase); anxiety, SMD = 0.93 reduction (95% CI, 3.26 reduction to 1.40 increase); pain, SMD = 0.01 increase (95% CI, 2.54 reduction to 2.56 increase); and depression, SMD = 0.40 reduction (95% CI, 6.50 reduction to 5.71 increase). Substantial heterogeneity was observed for anxiety, pain, and depression outcomes (I-squared above 80%). The authors note that these findings reflect insufficient statistical power and high heterogeneity rather than evidence of a lack of benefit; that the small number of studies, diversity of interventions, and differences in follow-up duration limit interpretability; and that larger, well-designed studies using standardized outcome measures are needed.

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