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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV0317

First-episode psychosis: the importance of a comprehensive medical evaluation

FIRST EPISODE PSYCHOSIS: THE IMPORTANCE OF A COMPREHENSIVE MEDICAL EXAM

A comprehensive medical evaluation is essential in patients presenting with first-episode psychosis to distinguish primary psychiatric disorders from secondary medical causes.

The aim is to review the importance of a comprehensive medical evaluation in patients presenting with first-episode psychosis (FEP); the poster identifies the first episode as a critical period that significantly influences the long-term course. The method is a literature review conducted in the PubMed and Google Scholar databases using the terms "first episode psychosis", "secondary psychosis", "medical causes of psychosis", "autoimmune encephalitis" and "neuropsychiatric disorders"; publications discussing medical etiologies and recommended diagnostic investigations were evaluated. No sample size, number of included studies or quantitative results were reported. The review reports that numerous medical conditions can present with psychotic symptoms, including autoimmune diseases such as anti-NMDA receptor encephalitis, infectious diseases, endocrine disorders, metabolic diseases, neurological lesions and substance-induced conditions. The recommended diagnostic evaluation includes laboratory investigations, toxicology screening, neuroimaging and, when indicated, electroencephalography or cerebrospinal fluid analysis. Failure to identify underlying medical causes can lead to delayed treatment and poor clinical outcomes. In conclusion, the review emphasizes that early recognition of underlying conditions may improve treatment outcomes and prevent misdiagnosis, highlighting the importance of raising clinicians' awareness of the medical differential diagnosis of psychosis.

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