# Reconceptualizing psychotic disorders within a cognition-first framework - URL: https://alisanburak.com/en/wcp-2026-posterler/so491 - Language: en - Last updated: not specified - Page title: Reconceptualizing psychotic disorders within a cognition-first framework | WCP 2026 Summary > Two independent meta-analyses of antipsychotic-naive patients show that cognitive impairment is present across all domains at the onset of psychosis, with cons… This page was translated automatically from Turkish. [Read the original](https://alisanburak.com/wcp-2026-posterler/so491) Bu sayfa, 26. Dünya Psikiyatri Kongresi'nde sunulan çalışmanın yapay zekâ desteğiyle hazırlanmış Türkçe özetidir. Çalışmanın sahibi sunan yazarlardır; atıf için orijinal kaynağa başvurun. SO491 Kısa Sözlü Poster SunumuPsikoz ve Şizofreniİki meta-analizin karşılaştırmalı değerlendirmesi # Reconceptualizing psychotic disorders within a cognition-first framework RECONCEPTUALIZING PSYCHOTIC DISORDERS THROUGH A COGNITIVE-FIRST FRAMEWORK Sunan: Helena Fatouros-Bergman Ülke: Sweden Oturum: 4580 - PARALLEL SHORT ORAL POSTER SESSIONS: PSYCHOSIS & SCHIZOPHRENIA - Part VI Tarih: Sat, 26.09.2026 Two independent meta-analyses of antipsychotic-naive patients show that cognitive impairment is present across all domains at the onset of psychosis, with consistent effect sizes, supporting the view that cognitive impairment is a core feature of the illness rather than an effect of medication. The study aimed to compare two meta-analyses examining cognitive performance in antipsychotic-naive (drug-naive) patients to assess the consistency, magnitude, and domain-specific pattern of cognitive impairment at the onset of psychosis relative to healthy controls. The meta-analyses compared were Fatouros-Bergman and colleagues (2014), which focused on schizophrenia spectrum disorders, and Lee and colleagues (2024), which focused on first-episode psychosis. Study 1 synthesized 23 studies identified through searches of PubMed and PsycInfo up to November 2012, while Study 2 synthesized 50 PubMed-indexed studies published up to September 2022; the same search terms were used, results were organized according to MATRICS cognitive domains, and effects were quantified using standardized mean differences or Hedges’ g. Both meta-analyses showed significant impairment across all cognitive domains; the pattern and magnitude of impairments were highly consistent, with the most pronounced deficits observed in speed of processing, verbal memory, and working memory (effect sizes of approximately -1.0 or greater in magnitude). The figure in the poster presents the effect sizes from the two studies side by side for executive functioning, visual memory, attention, working memory, speed of processing, and verbal memory. The convergence of findings from research conducted across two different decades supports the view that cognitive impairment predates antipsychotic treatment and is a core feature of psychosis. In conclusion, cognition may be considered not merely a consequence of the illness but a primary dimension for staging, prognosis, and intervention; a cognition-first framework may pave the way for preventive strategies aimed at early identification and preserving functioning beyond symptom reduction. [Orijinal postere git](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/285) Bu çalışmaya nasıl atıf yapılır? APA 7: Fatouros-Bergman, H., et al. (2026, September 26). Reconceptualizing psychotic disorders through a cognitive-first framework [Poster presentation]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/285 Vancouver: Fatouros-Bergman H, et al. Reconceptualizing psychotic disorders through a cognitive-first framework [poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/285 Yazar adları ve başlık biçimi kongre sisteminden otomatik oluşturulmuştur; kullanmadan önce orijinal posterle karşılaştırın. ## Aynı konudan - [İlk atak psikoz ve esrar kullanım bozukluğu olan gençlerde yardım arama: Back to Reality video oyun serisinden çıkarımlar](https://alisanburak.com/en/wcp-2026-posterler/ev0002) - [Kimyasal bağımlılığın eşlik ettiği tedaviye dirençli şizofreni hastalarında modern antipsikotiklerin kombine kullanımının klinik sonuçları](https://alisanburak.com/en/wcp-2026-posterler/ev0014) - [Şizofrenide bilişsel gerileme: Sosyal işlevsellik üzerindeki etkisi ve bilişsel iyileştirme olanakları](https://alisanburak.com/en/wcp-2026-posterler/ev0018) - [Ağır kişilerarası şiddet öyküsü olan, şizofrenisi olan ve olmayan bireylerde temel benlik bozukluklarının karşılaştırılması](https://alisanburak.com/en/wcp-2026-posterler/ev0103) - [Yoğun çakra odaklı meditasyonla ilişkili bir ergende akut ve geçici psikotik bozukluk: olgu sunumu](https://alisanburak.com/en/wcp-2026-posterler/ev0231) [Tüm WCP 2026 özetleri](https://alisanburak.com/en/wcp-2026-posterler) --- Kaynak / Source: https://alisanburak.com/en/wcp-2026-posterler/so491 İletişim / Contact: Bağdat Caddesi, Veli Güneysu Apt. 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