# Association of peripheral inflammatory indices with symptom severity, functioning, and metabolic parameters in a population diagnosed with schizophrenia in Mexico - URL: https://alisanburak.com/en/wcp-2026-posterler/so411 - Language: en - Last updated: not specified - Page title: Association of peripheral inflammatory indices with symptom severity, functioning, and metabolic parameters in a population diagnosed with schizophrenia in Mexico | WCP 2026 Summary > In clinically stable patients with schizophrenia, peripheral inflammatory indices were associated with glycemic and lipid parameters, but not with symptom seve… This page was translated automatically from Turkish. [Read the original](https://alisanburak.com/wcp-2026-posterler/so411) This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it. SO411 Brief Oral Poster PresentationPsychosis and SchizophreniaCross-sectional study # Association of peripheral inflammatory indices with symptom severity, functioning, and metabolic parameters in a population diagnosed with schizophrenia in Mexico ASSOCIATION OF PERIPHERAL INFLAMMATORY INDICES WITH SYMPTOM SEVERITY, FUNCTIONING, AND METABOLIC PARAMETERS IN THE MEXICAN POPULATION DIAGNOSED WITH SCHIZOPHRENIA. Presenter: Hector E. Guzman Country: Mexico Institution: Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Session: 4450 - PARALLEL SHORT ORAL POSTER SESSIONS: PSYCHOSIS & SCHIZOPHRENIA - Part V Date: Sat, 26.09.2026 In clinically stable patients with schizophrenia, peripheral inflammatory indices were associated with glycemic and lipid parameters, but not with symptom severity or functioning. The study aimed to evaluate the associations of peripheral inflammatory indices (PII) with symptom severity, psychosocial functioning, and metabolic parameters in Mexican patients with schizophrenia receiving routine clinical follow-up. A total of 100 clinically stable outpatients aged 18 years or older who had not been hospitalized within the past year were assessed at the Instituto Nacional de Psiquiatría in Mexico City; exclusion criteria included clozapine use, autoimmune, hematological, oncological, and immunodeficiency conditions, and immunomodulatory treatment. The Positive and Negative Syndrome Scale (PANSS), Functioning Assessment Short Test (FAST), and Calgary Depression Scale for Schizophrenia (CDSS) were administered. Complete blood count, lipid profile, fasting glucose, and HbA1c data from the preceding 12 months were used to calculate the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI). Spearman partial rank correlations adjusted for body mass index, age, olanzapine-equivalent dose, and smoking were used. Of the sample, 66% were male; the median age was 44.0 years (IQR 19.8), the median age at onset was 23.5 years (IQR 11.3), and the median illness duration was 17.0 years (IQR 18.3). PII values showed no significant associations with PANSS, FAST, or CDSS scores. Positive correlations were found between HbA1c and SII (rs = 0.242; p = 0.017), AISI (rs = 0.256; p = 0.012), and SIRI (rs = 0.229; p = 0.025). Triglyceride levels were negatively correlated with NLR (rs = −0.246; p = 0.016), PLR (rs = −0.256; p = 0.012), MLR (rs = −0.260; p = 0.011), and SII (rs = −0.219; p = 0.032). The authors note that, in clinically stable patients, these indices are associated with glycemic and lipid changes rather than symptom severity or functioning, and that SII and AISI in particular could serve as accessible immunometabolic biomarkers. [View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/806) How to cite this study APA 7: Guzman, H. E., et al. (2026, September 26). Association of peripheral inflammatory indices with symptom severity, functioning, and metabolic parameters in the mexican population diagnosed with schizophrenia [Poster presentation]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/806 Vancouver: Guzman HE, et al. Association of peripheral inflammatory indices with symptom severity, functioning, and metabolic parameters in the mexican population diagnosed with schizophrenia [poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. 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