# Pharmacoepidemiology and clinical correlates of antipsychotic use in the treatment of delirium at a tertiary care hospital

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- Page title: Pharmacoepidemiology and clinical correlates of antipsychotic use in the treatment of delirium at a tertiary care hospital | WCP 2026 Summary

> Antipsychotic selection and dosing in delirium vary substantially according to comorbidities and physiological variables, highlighting the need for individuali…

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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

SO345

Brief Oral Poster PresentationPsychopharmacologyRetrospective study

# Pharmacoepidemiology and clinical correlates of antipsychotic use in the treatment of delirium at a tertiary care hospital

PHARMACOEPIDEMIOLOGY AND CLINICAL CORRELATES OF ANTIPSYCHOTIC TREATMENT FOR DELIRIUM IN A TERTIARY CARE HOSPITAL

Presenter: Priabprat Jansem

Country: Thailand

Institution: Prince of Songkla University, Faculty of Medicine, Department of Psychiatry

Session: 3860 - PARALLEL SHORT ORAL POSTER SESSIONS: CONSULTATION LIAISON - Part III

Date: Fri, 25.09.2026

Antipsychotic selection and dosing in delirium vary substantially according to comorbidities and physiological variables, highlighting the need for individualized prescribing.

The study aimed to examine antipsychotic selection and dosing patterns, along with the clinical variables associated with these prescribing decisions, in delirium—a condition whose management remains controversial—at a tertiary care hospital. Electronic medical records of adult inpatients who received antipsychotics for delirium in Thailand between 2021 and 2025 were reviewed retrospectively; analyses used odds ratios (ORs), the Kruskal–Wallis test, and Spearman’s rank correlation coefficient. A total of 353 admissions were examined; the mean age was 75.7 years (SD=12.9), 66.9% of patients were male, and 54.4% had a high comorbidity burden (Charlson Comorbidity Index, CCI>5). The most frequently prescribed antipsychotic was quetiapine (64%), followed by haloperidol (57%), risperidone (19%), and aripiprazole (14%); no extrapyramidal adverse effects were reported (as stated in the abstract). Risperidone was used less frequently in patients with a high CCI (OR 0.41, p=0.027) or abnormal blood urea nitrogen (BUN) levels (OR 0.54, p=0.024), whereas aripiprazole was used more frequently in those with abnormal zinc levels (OR 1.88, p=0.05) or anemia (OR 4.43, p=0.042); surgery and general anesthesia were associated with less frequent quetiapine use and more frequent aripiprazole use. Olanzapine use was associated with in-hospital mortality (OR 4.26, p=0.016); quetiapine doses were higher in patients with vascular dementia (46.1 mg/day, p=0.045), whereas haloperidol doses were lower in those with abnormal BUN levels, dysnatremia, hypoalbuminemia, or exposure to anesthesia (all p<0.05). Regimen changes were positively associated with aripiprazole dose and negatively associated with haloperidol dose; a negative correlation was found between haloperidol dose and length of hospital stay (r=−0.168, p=0.018). The findings emphasize that antipsychotic selection and dosing in delirium should be individualized and tailored to the clinical context.

[View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/779)

How to cite this study

APA 7: Jansem, P., et al. (2026, September 25). Pharmacoepidemiology and clinical correlates of antipsychotic treatment for delirium in a tertiary care hospital [Poster presentation]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/779

Vancouver: Jansem P, et al. Pharmacoepidemiology and clinical correlates of antipsychotic treatment for delirium in a tertiary care hospital [poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/779

Author names and title formatting were generated automatically from the congress system; please check them against the original poster before use.

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