# Braining: a pragmatic randomized trial of exercise in routine psychiatric care, effects on mental and metabolic health - URL: https://alisanburak.com/en/wcp-2026-posterler/so343 - Language: en - Last updated: not specified - Page title: Braining: a pragmatic randomized trial of exercise in routine psychiatric care, effects on mental and metabolic health | WCP 2026 Summary > Structured group exercise was feasible and well tolerated in routine psychiatric care, but was not superior to structured physical activity support in reducing… This page was translated automatically from Turkish. [Read the original](https://alisanburak.com/wcp-2026-posterler/so343) This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it. SO343 Brief Oral Poster PresentationSleep and LifestyleRCT # Braining: a pragmatic randomized trial of exercise in routine psychiatric care, effects on mental and metabolic health BRAINING: A PRAGMATIC RANDOMISED TRIAL OF EXERCISE IN ROUTINE PSYCHIATRIC CARE—EFFECTS ON MENTAL AND METABOLIC HEALTH Presenter: Åsa S. Anger Country: Sweden Session: 3720 - PARALLEL SHORT ORAL POSTER SESSIONS: LIFESTYLE & SLEEP Date: Fri, 25.09.2026 Structured group exercise was feasible and well tolerated in routine psychiatric care, but was not superior to structured physical activity support in reducing depressive symptoms. The aim was to evaluate the effectiveness of Braining, a structured exercise program developed collaboratively by patients and clinicians and integrated into routine psychiatric care in Stockholm, Sweden, in improving health outcomes. This multicenter randomized controlled trial (RCT), conducted at four psychiatric outpatient clinics, enrolled 211 physically inactive adult patients, who were randomized 1:1, stratified by site, to Braining (n=107) or an active control consisting of structured physical activity support (SPAS; referred to in the abstract as structured advice on PA, SAPA). The intervention consisted of 30- to 45-minute group-based aerobic interval exercise sessions led by trained psychiatric staff and motivational components; participants were followed monthly for 12 weeks and additionally at 6 and 12 months. The primary outcomes were moderate-to-vigorous physical activity (MVPA), measured using ActivPAL, and depressive symptoms, measured using the Patient Health Questionnaire-9 (PHQ-9). Intention-to-treat analyses were performed using a linear mixed model with random slopes and intercepts and constrained longitudinal data analysis. Women accounted for 73% of participants in the Braining group and 70% in the control group; mean ages were 39.5 (SD 12.9) and 41.4 (SD 12.7) years, respectively. Common diagnoses were neurodevelopmental disorders (55% and 70%), depression (52% and 57%), any anxiety disorder (54% and 55%), and post-traumatic stress disorder (34% and 26%). The mean baseline PHQ-9 score was 13.2 (SD 5.6; range 1 to 25), and estimated PHQ-9 scores decreased in both groups over 12 weeks, with no statistically significant between-group difference in change (mean difference 0.58 points; 95% confidence interval -0.80 to 1.96; p=0.41). At baseline, 25% of participants met the criteria for metabolic syndrome (at least 3 metabolic risk factors). The intervention was well tolerated, with four mild adverse events reported in the Braining group. In conclusion, Braining is a feasible and well-tolerated intervention in routine psychiatric care; the absence of a significant between-group difference highlights both the potential and the challenges of translating exercise interventions into real-world clinical practice. Analyses of metabolic outcomes, the remaining psychiatric outcomes, and long-term follow-up are ongoing. [View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1845) How to cite this study APA 7: Anger, Å. S., et al. (2026, September 25). Braining: a pragmatic randomised trial of exercise in routine psychiatric care—effects on mental and metabolic health [Poster presentation]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1845 Vancouver: Anger ÅS, et al. Braining: a pragmatic randomised trial of exercise in routine psychiatric care—effects on mental and metabolic health [poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. 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