# Treatment approaches for polycystic ovary syndrome and co-occurring psychiatric disorders: a systematic review

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- Page title: Treatment approaches for polycystic ovary syndrome and co-occurring psychiatric disorders: a systematic review | WCP 2026 Summary

> Combined treatment approaches addressing both the metabolic and psychiatric dimensions of polycystic ovary syndrome are associated with better psychiatric outc…

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# Treatment approaches for polycystic ovary syndrome and co-occurring psychiatric disorders: a systematic review

Therapeutic approaches in polycystic ovary syndrome and associated psychiatric disorders: a systematic review

Sunan: Yasmin M. Suleiman

Ülke: Brazil

Oturum: 3821 - FREE COMMUNICATIONS 14: SUICIDE PREVENTION AND PUBLIC HEALTH STRATEGIES

Tarih: Fri, 25.09.2026, 13:30 - 13:40

Salon: Hall K16

Combined treatment approaches addressing both the metabolic and psychiatric dimensions of polycystic ovary syndrome are associated with better psychiatric outcomes than interventions used alone.

The aim is to evaluate the effectiveness of pharmacological and nonpharmacological interventions in improving psychiatric outcomes in patients with polycystic ovary syndrome (PCOS). In this systematic review conducted according to PRISMA guidelines, the PubMed, Scopus, and SciELO databases were searched for studies published between 2000 and 2026; randomized clinical trials, cohort studies, and systematic reviews evaluating psychiatric outcomes in patients with PCOS were included, while studies focusing exclusively on reproductive outcomes were excluded. A total of 24 studies met the inclusion criteria. Combined treatment approaches showed superior outcomes compared with isolated interventions; lifestyle interventions involving diet and physical activity were associated with improvements in depressive and anxiety symptoms. Pharmacological treatments such as metformin demonstrated benefits not only for metabolic parameters but also for mood, possibly through modulation of insulin resistance; combined oral contraceptives indirectly contributed to psychological well-being through hormonal regulation; and cognitive behavioral therapy was found to be effective in reducing psychiatric symptoms, particularly when integrated into multidisciplinary care. Emerging evidence was reported suggesting that glucagon-like peptide-1 receptor agonists may benefit both metabolic and psychological outcomes; the authors concluded that routine early psychiatric screening should be incorporated into PCOS follow-up care to reduce the long-term burden of disease.

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APA 7: Suleiman, Y. M., et al. (2026, September 25). Therapeutic approaches in polycystic ovary syndrome and associated psychiatric disorders: a systematic review [Oral presentation]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden.

Vancouver: Suleiman YM, et al. Therapeutic approaches in polycystic ovary syndrome and associated psychiatric disorders: a systematic review [oral presentation]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden.

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