# Treatment approach in acute psychosis with catatonic features: from diazepam and cannabidiol to full remission with lorazepam - URL: https://alisanburak.com/en/wcp-2026-posterler/ev1127 - Language: en - Last updated: not specified - Page title: Treatment approach in acute psychosis with catatonic features: from diazepam and cannabidiol to full remission with lorazepam | WCP 2026 Summary > Full remission was achieved with injectable lorazepam 4 mg/day in acute psychosis with catatonic features unresponsive to antipsychotics. This page was translated automatically from Turkish. [Read the original](https://alisanburak.com/wcp-2026-posterler/ev1127) This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it. EV1127 E-PosterPsychopharmacologyCase Report # Treatment approach in acute psychosis with catatonic features: from diazepam and cannabidiol to full remission with lorazepam THERAPEUTIC APPROACH TO ACUTE PSYCHOSIS WITH CATATONIC FEATURES: FROM DIAZEPAM AND CBD TO FULL REMISSION VIA LORAZEPAM Presenter: Georgia-Nektaria Porfyri Country: Greece Institution: General Hospital of Argolida, Department of Psychiatry Full remission was achieved with injectable lorazepam 4 mg/day in acute psychosis with catatonic features unresponsive to antipsychotics. The aim of this presentation is to describe the clinical management of a complex symptom profile involving co-occurring catatonia, dissociative stupor, and autonomic dysfunction in late adolescence. A 17-year-old female patient presenting with selective mutism, refusal of food and fluids, and autonomic instability was admitted to an adult psychiatric unit; nasogastric tube placement was required due to tachycardia and urinary retention. Initial antipsychotic trials (olanzapine 15 mg, haloperidol 10 mg, paliperidone 5 mg) produced a poor clinical response. Diazepam 40 mg/day, used as bridging therapy, provided a partial response and partial restoration of mobility, while adjunctive 20% cannabidiol (CBD) at 3 cc/day provided anxiolytic support. Full remission was achieved with injectable lorazepam 4 mg/day, with resolution of catatonia and restoration of speech and vital functions. Following remission, command auditory hallucinations associated with food refusal emerged, confirming an underlying psychotic process. The authors emphasize that benzodiazepines remain the gold standard for acute catatonia, that high-dose diazepam may provide a stabilizing bridge when medication access is limited, and that a rapid response may reveal the underlying psychotic disorder. [View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1305) How to cite this study APA 7: Porfyri, G-N., et al. (2026, September 23-26). Therapeutic approach to acute psychosis with catatonic features: from diazepam and cbd to full remission via lorazepam [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1305 Vancouver: Porfyri GN, et al. Therapeutic approach to acute psychosis with catatonic features: from diazepam and cbd to full remission via lorazepam [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1305 Author names and title formatting were generated automatically from the congress system; please check them against the original poster before use. ## On the same topic - [Açığı kapatmak: erişkin DEHB ilacı başlanmadan önce EKG sevk uyumunun iyileştirilmesi, kapalı döngü klinik denetim](https://alisanburak.com/en/wcp-2026-posterler/ev0088) - [Anksiyete bozukluğu olan hastalarda psikobiyotik müdahalesi: ısıl işlem görmüş Lactobacillus paracasei PS23'ün etkilerini inceleyen çift kör randomize kontrollü çalışma](https://alisanburak.com/en/wcp-2026-posterler/ev0126) - [Otizm spektrum bozukluğunda bumetanidin tedavi edici potansiyeli: güncel kanıtlar ve gelecek yönelimleri](https://alisanburak.com/en/wcp-2026-posterler/ev0157) - [Verbaskozid ile otizm spektrum bozukluğu tedavisinin mekanizmaları: ağ farmakolojisi, moleküler yerleştirme ve moleküler dinamik temelli inceleme](https://alisanburak.com/en/wcp-2026-posterler/ev0172) - [Otizm spektrum bozukluğunun çekirdek belirtilerinin tedavisinde kannabidiol: sistematik derleme](https://alisanburak.com/en/wcp-2026-posterler/ev0186) [All WCP 2026 summaries](https://alisanburak.com/en/wcp-2026-posterler) --- Kaynak / Source: https://alisanburak.com/en/wcp-2026-posterler/ev1127 İletişim / Contact: Bağdat Caddesi, Veli Güneysu Apt. No:453 K:4 D:9, Suadiye / Kadıköy, İstanbul · +90 532 642 95 25 · info@alisanburak.com · https://alisanburak.com/bagdat-caddesi-psikoterapi-iletisim