# Ketamine for persistent suicidal ideation in treatment-resistant depression following electroconvulsive therapy: a case report and literature review

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- Page title: Ketamine for persistent suicidal ideation in treatment-resistant depression following electroconvulsive therapy: a case report and literature review | WCP 2026 Summary

> In a young man who did not respond to electroconvulsive therapy, eight intravenous ketamine infusions eliminated suicidal ideation but produced only a limited…

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Bu sayfa, 26. Dünya Psikiyatri Kongresi'nde sunulan çalışmanın yapay zekâ desteğiyle hazırlanmış Türkçe özetidir. Çalışmanın sahibi sunan yazarlardır; atıf için orijinal kaynağa başvurun.

EV1077

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# Ketamine for persistent suicidal ideation in treatment-resistant depression following electroconvulsive therapy: a case report and literature review

KETAMINE FOR PERSISTENT SUICIDAL IDEATION IN TREATMENT-RESISTANT DEPRESSION FOLLOWING ECT: A CASE REPORT AND LITERATURE REVIEW

Sunan: Duaa Fatima

Ülke: Pakistan

Kurum: Faisalabad Medical University, Allied Hospital II, Department of Psychiatry and Behavioral Sciences

In a young man who did not respond to electroconvulsive therapy, eight intravenous ketamine infusions eliminated suicidal ideation but produced only a limited reduction in depression severity.

The aim is to discuss the role of ketamine in treatment-resistant depression (TRD) with persistent suicidal ideation following electroconvulsive therapy (ECT), using a case report; the poster states that depression affects up to 19.62% of the population in Pakistan. The method is a single case report of a 19-year-old single male patient diagnosed with major depressive disorder according to DSM-5 criteria, with a 7-year history of persistent depressive symptoms. The patient had received trials of dosulepin, bupropion, lithium, and amitriptyline at adequate doses and for adequate durations according to the Maudsley Reçeteleme Kılavuzu (Maudsley Prescribing Guidelines); assessment identified borderline personality traits, and baseline investigations were normal. The patient, who was taking venlafaxine, lithium, and mirtazapine before ECT, received 10 sessions of bilateral ECT over 5 weeks, with no adverse effects observed. When severe depressive symptoms and suicidal ideation persisted after ECT (HAM-D 33), intravenous ketamine was administered at a dose of 0.5 mg/kg over 40 minutes, twice weekly for four weeks. After eight ketamine infusions, suicidal ideation resolved, and sleep, appetite, and energy improved; however, anhedonia, hopelessness, and low self-esteem persisted, and the HAM-D score decreased from 33 to 30. In conclusion, this case illustrates the complexity of managing TRD in young adults, reporting that ketamine infusions were associated with the resolution of suicidal ideation, although the overall reduction in depression severity remained limited, and that ketamine may be a useful adjunctive treatment for reducing suicidality in patients with persistent depression following ECT. Written informed consent for publication was obtained from the patient.

[Orijinal postere git](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1553)

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APA 7: Fatima, D., et al. (2026, September 23-26). Ketamine for persistent suicidal ideation in treatment-resistant depression following ect: a case report and literature review [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1553

Vancouver: Fatima D, et al. Ketamine for persistent suicidal ideation in treatment-resistant depression following ect: a case report and literature review [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1553

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