# Prescribing patterns of long-acting injectable antipsychotics in older adults: a retrospective study

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- Page title: Prescribing patterns of long-acting injectable antipsychotics in older adults: a retrospective study | WCP 2026 Summary

> Most of the 38 patients over the age of 65 receiving long-acting injectable antipsychotics in Qatar were fully adherent to treatment, and 76.3% achieved stabil…

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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV0956

E-PosterGeriatricsRetrospective descriptive study

# Prescribing patterns of long-acting injectable antipsychotics in older adults: a retrospective study

PRESCRIBING PATTERNS OF LONG-ACTING ANTIPSYCHOTICS INJECTIONS AMONG OLDER ADULTS: A RETROSPECTIVE STUDY

Presenter: Shatha Alqam

Country: Qatar

Institution: Hamad Medical Corporation, Mental Health Service

Most of the 38 patients over the age of 65 receiving long-acting injectable antipsychotics in Qatar were fully adherent to treatment, and 76.3% achieved stabilization.

The study aimed to assess prescribing patterns of long-acting injectable antipsychotics (LAIs) in the geriatric population in Qatar, which had not previously been investigated, and to compare current clinical practice with international guidelines on safe prescribing. This retrospective quantitative chart review, conducted at Hamad Medical Corporation Mental Health Services between 01.01.2024 and 01.01.2025, included all individuals aged 65 years and older with severe mental illness who were receiving LAIs; data were analyzed using descriptive statistics in SPSS version 29. Of the 38 patients identified, 60.53% were aged 65–69 years (n=23), 23.68% were aged 70–74 years (n=9), and 10.53% were aged 75–79 years (n=4); 55.2% were male and 73.6% were Qatari nationals. In 31 patients (81.58%), the duration of psychiatric illness exceeded 10 years. The most commonly administered medication was paliperidone palmitate in a one-month or three-month formulation (44.7%; n=17), followed by zuclopenthixol every two to three weeks (21.5%; n=8) and flupentixol every two to four weeks (18.4%; n=7); all patients were prescribed antipsychotics below the maximum recommended dose. The indication was schizophrenia in 57.9% of patients (n=22) and bipolar disorder in 36.8% (n=14); the reason for switching to an LAI was recorded as poor adherence to oral treatment in 21.05% and was undocumented in 78.95%. Overall, 94.74% of patients were fully adherent to treatment, and 76.32% achieved stabilization (remission) with LAIs; 13.2% showed symptom improvement, 5.3% showed no change, and 5.3% experienced deterioration. Medication was discontinued in 23.7% (8 patients for efficacy-related reasons and 1 patient because of a renal issue). Reported adverse drug reactions included extrapyramidal side effects (n=3; 7.89%), hyperprolactinemia (n=2; 5.26%), hand tremor (n=1; 2.63%), and elevated blood glucose (n=1; 2.63%); half of the prescribers (n=19; 50%) were specialist physicians. The authors note that randomized evidence on LAI use in the geriatric population remains limited. They highlight cautious dosing, individualized selection based on previous response and comorbidities, regular monitoring (metabolic panels, extrapyramidal symptom scales, and ECG and prolactin testing when indicated), and a preference for second-generation LAIs when aiming to reduce extrapyramidal risk as key considerations in clinical practice. They emphasize that adherence benefits must be balanced against agent-specific safety profiles, particularly in older adults with dementia.

[View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1494)

How to cite this study

APA 7: Alqam, S., et al. (2026, September 23-26). Prescribing patterns of long-acting antipsychotics injections among older adults: a retrospective study [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1494

Vancouver: Alqam S, et al. Prescribing patterns of long-acting antipsychotics injections among older adults: a retrospective study [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1494

Author names and title formatting were generated automatically from the congress system; please check them against the original poster before use.

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