# Catatonia as the first manifestation of cerebral venous thrombosis: a case report highlighting diagnostic and treatment challenges in a resource-limited setting

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> Acute catatonia in a young woman with no psychiatric history emerged as the first and only manifestation of cerebral venous sinus thrombosis.

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Bu sayfa, 26. Dünya Psikiyatri Kongresi'nde sunulan çalışmanın yapay zekâ desteğiyle hazırlanmış Türkçe özetidir. Çalışmanın sahibi sunan yazarlardır; atıf için orijinal kaynağa başvurun.

EV0872

E-PosterKonsültasyon-LiyezonOlgu sunumu

# Catatonia as the first manifestation of cerebral venous thrombosis: a case report highlighting diagnostic and treatment challenges in a resource-limited setting

CATATONIA AS AN INITIAL PRESENTATION OF CEREBRAL VENOUS THROMBOSIS: A CASE REPORT HIGHLIGHTING CHALLENGES IN DIAGNOSIS AND MANAGEMENT IN A RESOURCE-POOR SETTING

Sunan: Mihiri Siribaddana

Ülke: Sri Lanka

Acute catatonia in a young woman with no psychiatric history emerged as the first and only manifestation of cerebral venous sinus thrombosis.

The aim of this report is to illustrate the diagnostic dilemma posed by cerebral venous sinus thrombosis (CVST), a rare and potentially fatal condition, presenting solely with psychiatric symptoms. A 26-year-old woman presented with a two-week history of reduced food intake, reduced speech, and social withdrawal. Shortly before admission, she developed acute fear, with a history of unprovoked laughing and crying, purposeless repetitive movements, and neglect of daily activities, self-care, and interests. Examination revealed generalized rigidity alongside catatonic signs, including staring, negativism, stupor, mutism, and catalepsy, with no focal neurological deficits. She had been diagnosed with Hashimoto thyroiditis six years earlier but had not continued treatment, and her thyroid function tests were abnormal. Investigations revealed a positive antinuclear factor (1:80), positive thyroid peroxidase (TPO) antibodies (403 IU/ml), negative screening for antiphospholipid syndrome and tuberculosis, and a normal EEG. MR venography showed chronic thrombosis of the left internal jugular vein, sigmoid sinus, and transverse sinus, while noncontrast CT revealed hyperdense foci in the U-fibers. Following the diagnosis of catatonia, oral diazepam was initiated because lorazepam was unavailable, resulting in clinical improvement; warfarin was administered for oral anticoagulation. When symptoms recurred after six months of treatment, the causes of thrombosis were reassessed, and the patient was treated with corticosteroids and azathioprine for suspected steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), which can also cause catatonia. Reported resource limitations included the unavailability of lorazepam, for which the evidence is stronger, delays of several months in obtaining MRI due to long waiting lists, and avoidance of electroconvulsive therapy because the etiology remained unclear. CVST accounts for 0.5% to 1% of all strokes and is more common in young women. Acute catatonia in a person with no previous psychiatric disorder warrants clinical suspicion and further investigation, particularly in this predisposed group.

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APA 7: Siribaddana, M., & Rathnaikege, P. (2026, September 23-26). Catatonia as an initial presentation of cerebral venous thrombosis: a case report highlighting challenges in diagnosis and management in a resource-poor setting [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1768

Vancouver: Siribaddana M, Rathnaikege P. Catatonia as an initial presentation of cerebral venous thrombosis: a case report highlighting challenges in diagnosis and management in a resource-poor setting [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1768

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