# Forgiveness, dignity, and hopelessness as therapeutic levers in major depression: A 2-year real-world follow-up study - URL: https://alisanburak.com/en/wcp-2026-posterler/ev0812 - Language: en - Last updated: not specified - Page title: Forgiveness, dignity, and hopelessness as therapeutic levers in major depression: A 2-year real-world follow-up study | WCP 2026 Summary > Antidepressant treatment combined with structured follow-up yielded sustained reductions in depressive symptoms, hopelessness, and dignity-related distress ove… This page was translated automatically from Turkish. [Read the original](https://alisanburak.com/wcp-2026-posterler/ev0812) Bu sayfa, 26. Dünya Psikiyatri Kongresi'nde sunulan çalışmanın yapay zekâ desteğiyle hazırlanmış Türkçe özetidir. Çalışmanın sahibi sunan yazarlardır; atıf için orijinal kaynağa başvurun. EV0812 E-PosterDuygudurum ve AnksiyeteGözlemsel izlem çalışması # Forgiveness, dignity, and hopelessness as therapeutic levers in major depression: A 2-year real-world follow-up study FORGIVENESS, DIGNITY AND HOPELESSNESS AS THERAPEUTIC LEVERS IN MAJOR DEPRESSION: A 2-YEAR REAL-WORLD FOLLOW-UP STUDY Sunan: Andreana Franza Ülke: Italy Antidepressant treatment combined with structured follow-up yielded sustained reductions in depressive symptoms, hopelessness, and dignity-related distress over 24 months, while forgiveness showed more limited changes over time. This observational study conducted in real-world settings aimed to evaluate the longitudinal role of forgiveness, dignity, and hopelessness in patients with major depressive disorder (MDD) over a 2-year follow-up. The study enrolled 83 patients (47 women, 36 men; mean age 47.4 +/- 15.2 years) diagnosed with MDD according to DSM-5-TR criteria and admitted to psychiatric residential rehabilitation centers in southern Italy; inclusion criteria were HAM-D >= 14 and PHQ-9 > 5. All patients received antidepressant treatment (paroxetine, clomipramine, or venlafaxine) at fixed therapeutic doses in addition to the usual rehabilitation program and were assessed at baseline (T0), 6 months (T1), 12 months (T2), and 24 months (T3) using the Hamilton Depression Rating Scale (HAM-D), Patient Health Questionnaire (PHQ-9), Heartland Forgiveness Scale (HFS, total score), Beck Hopelessness Scale (BHS), and Patient Dignity Inventory (PDI); analyses used descriptive statistics and paired comparisons (paired t-tests). Depressive symptoms decreased progressively and significantly: HAM-D scores fell from 29.85 +/- 7.68 to 23.69 +/- 7.10, 19.51 +/- 6.77, and 15.64 +/- 5.61, respectively; PHQ-9 scores declined from 14.82 +/- 5.59 to 11.61 +/- 4.95, 7.77 +/- 5.03, and 7.64 +/- 4.07 (p < 0.001 for both). Hopelessness (BHS, from 8.96 +/- 3.83 to 4.64 +/- 3.66; p < 0.001) and dignity-related distress (PDI, from 60.16 +/- 20.16 to 52.75 +/- 15.60; p < 0.001) also improved significantly, while the reduction in total HFS scores was smaller (from 65.81 +/- 23.66 to 60.36 +/- 21.19; p = 0.037), and subscale analyses are ongoing. In conclusion, antidepressant treatment combined with structured follow-up in a rehabilitation setting was associated with clinically meaningful and sustained improvement over 24 months, whereas the trajectory of dispositional forgiveness appeared more complex. [Orijinal postere git](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/603) Bu çalışmaya nasıl atıf yapılır? APA 7: Franza, F., Franza, A., Solomita, B., Litta, A., Vacca, A., Minò, M. V., & Tavormina, G. (2026, September 23-26). Forgiveness, dignity and hopelessness as therapeutic levers in major depression: a 2-year real-world follow-up study [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/603 Vancouver: Franza F, Franza A, Solomita B, Litta A, Vacca A, Minò MV, et al. Forgiveness, dignity and hopelessness as therapeutic levers in major depression: a 2-year real-world follow-up study [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/603 Yazar adları ve başlık biçimi kongre sisteminden otomatik oluşturulmuştur; kullanmadan önce orijinal posterle karşılaştırın. ## Aynı konudan - [Dikkat eksikliği hiperaktivite bozukluğu olan beliren yetişkinlerde biriktiricilik belirtileri ve davranışları](https://alisanburak.com/en/wcp-2026-posterler/ev0068) - [Tanı konmamış erişkin dikkat eksikliği/hiperaktivite bozukluğunun anksiyete ve depresif bozukluklar için sürdürücü etken olması: bir literatür derlemesi](https://alisanburak.com/en/wcp-2026-posterler/ev0069) - [DEHB, mükemmeliyetçilik ve öz şefkat: olumsuz duygulanıma giden yollar](https://alisanburak.com/en/wcp-2026-posterler/ev0083) - [Anksiyete ile ilişkili bozukluklarda kendi kendine yönlendirilen sanal gerçeklik terapisinin etkililiği: sistematik derleme ve meta-analiz](https://alisanburak.com/en/wcp-2026-posterler/ev0109) - [Birinci basamakta orta şiddette yaygın anksiyete bozukluğunda bilişsel davranışçı terapinin SSGİ ile karşılaştırılması: kontrollü klinik çalışma](https://alisanburak.com/en/wcp-2026-posterler/ev0110) [Tüm WCP 2026 özetleri](https://alisanburak.com/en/wcp-2026-posterler) --- Kaynak / Source: https://alisanburak.com/en/wcp-2026-posterler/ev0812 İletişim / Contact: Bağdat Caddesi, Veli Güneysu Apt. 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