# Melanoma, mania, and medical decision-making: a case of impaired capacity in an older adult

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- Page title: Melanoma, mania, and medical decision-making: a case of impaired capacity in an older adult | WCP 2026 Summary

> Although the ability to express a choice appeared preserved in an older patient with mania who refused oncological treatment, understanding, appreciation, and…

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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV0607

E-PosterConsultation-Liaison PsychiatryCase Report

# Melanoma, mania, and medical decision-making: a case of impaired capacity in an older adult

MELANOMA, MANIA, AND MEDICAL DECISION-MAKING: A CASE OF LOSS OF CAPACITY IN AN OLDER ADULT

Presenter: Heidi L. Kiziah

Country: United States of America

Institution: University of Miami/Jackson Health System, Department of Psychiatry and Behavioral Sciences

Although the ability to express a choice appeared preserved in an older patient with mania who refused oncological treatment, understanding, appreciation, and reasoning were impaired; capacity was restored after her condition improved.

The aim is to discuss, through a case report, the importance of a detailed assessment of decision-making capacity in patients with cancer whose refusal of treatment carries a serious risk of harm. The poster emphasizes that capacity is domain-, task-, and time-specific and that the threshold for capacity rises as the risk associated with a decision increases. It uses the four criteria proposed by Appelbaum and Grisso in 1988 as a framework: communicating a consistent choice, understanding relevant information, appreciating the situation and the personal significance of the information, and reasoning through the rational processing of information. The case concerns a 77-year-old woman receiving care for melanoma who was readmitted multiple times after repeatedly missing oncology follow-up appointments; a psycho-oncology consultation was requested because of anxiety and delusions. Psychiatric assessment revealed a severe mania-like presentation characterized by irritability, pressured and tangential speech, impaired attention, limited insight, and paranoid ideation directed toward healthcare professionals. Assessment of the affected domains found the ability to communicate a choice to be partially preserved: the patient could express a choice, but it remained inconsistent over time and across interactions with different people. Understanding, appreciation, and reasoning were judged to be impaired, and the patient was found to lack capacity to refuse oncological treatment. Following improvement in her medical condition and initiation of olanzapine, the patient regained capacity and was discharged without complications. The section on confounding factors recommends separately assessing psychosis, neurocognitive disorders, mania, health literacy, delirium, medication effects, and physiological causes. In conclusion, the poster emphasizes the need for critical, in-depth assessment of capacity using additional questions in high-risk settings such as oncology, as well as frequent reassessment, because capacity is a dynamic concept that can vary over time and across domains.

[View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/2146)

How to cite this study

APA 7: Kiziah, H. L., Goncalves, E. S., Muñoz-Abraham, O., Espinel, Z., & Rueda-Lara, M. A. (2026, September 23-26). Melanoma, mania, and medical decision-making: a case of loss of capacity in an older adult [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/2146

Vancouver: Kiziah HL, Goncalves ES, Muñoz-Abraham O, Espinel Z, Rueda-Lara MA. Melanoma, mania, and medical decision-making: a case of loss of capacity in an older adult [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/2146

Author names and title formatting were generated automatically from the congress system; please check them against the original poster before use.

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