# Spousal concordance in depressive symptoms and subsequent cognitive impairment and mortality: evidence from the China Health and Retirement Longitudinal Study

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- Page title: Spousal concordance in depressive symptoms and subsequent cognitive impairment and mortality: evidence from the China Health and Retirement Longitudinal Study | WCP 2026 Summary

> An individual's own depressive symptoms determine the risk of mild cognitive impairment; the spouse's symptoms or couple-level symptom concordance confer no ad…

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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV0410

E-PosterPublic Health and EpidemiologyCohort

# Spousal concordance in depressive symptoms and subsequent cognitive impairment and mortality: evidence from the China Health and Retirement Longitudinal Study

SPOUSAL CONCORDANCE IN DEPRESSIVE SYMPTOMS AND THE FOLLOWING COGNITIVE IMPAIRMENT AND MORTALITY: EVIDENCE FROM THE CHINA HEALTH AND RETIREMENT LONGITUDINAL STUDY

Presenter: Xuechun Wang

Country: China

Institution: Peking University Sixth Hospital

An individual's own depressive symptoms determine the risk of mild cognitive impairment; the spouse's symptoms or couple-level symptom concordance confer no additional risk and are not associated with all-cause mortality.

The study aimed to characterize the joint patterns of depressive symptoms over time in married couples and to investigate whether spousal concordance in symptoms confers a risk of mild cognitive impairment (MCI) and mortality beyond that associated with an individual's own symptoms. Among the 17,708 participants enrolled in CHARLS in 2011 and followed between 2011 and 2020, those without a spouse or with missing marital status information (N=2,798), those younger than 45 years (N=577), those with missing baseline CES-D-10 scores (N=1,549), and those with missing data on confounding variables (N=1,449) were excluded, leaving 11,912 married adults aged 45 years and older for analysis; a CES-D-10 score of 10 or higher was used as the threshold for depressive symptoms, and joint trajectory analysis, Cox regression, the Fine–Gray model, and mixed-effects models were used. Four stable trajectories were identified: low/low, 50.29%; high/mild, 21.25%; mild/high, 20.92%; and high/high, 7.54%. The distribution of baseline symptom groups was reported as 18.91% for both spouses, 16.26% for the participant only, 16.16% for the spouse only, and 48.67% for neither. The adjusted hazard ratio (HR) for incident MCI was 1.22 (95% confidence interval, 1.08 to 1.38) in the group in which both spouses had symptoms, 1.25 (1.10 to 1.42) in the participant-only group, and 0.94 (0.82 to 1.07) in the spouse-only group. No additional risk was observed when the group in which both spouses had symptoms was compared with the participant-only group (HR 0.98, P=0.73), and neither spousal symptoms nor the interaction between participant and spousal symptoms was significant. No overall difference in all-cause mortality was found between the groups (P=0.74). The findings indicate that, among middle-aged and older married individuals, an individual's own depressive symptoms are the determining factor for cognitive outcomes, and that spousal symptoms or couple-level concordance should not be considered independent risk indicators.

[View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1595)

How to cite this study

APA 7: Wang, X. (2026, September 23-26). Spousal concordance in depressive symptoms and the following cognitive impairment and mortality: evidence from the china health and retirement longitudinal study [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1595

Vancouver: Wang X. Spousal concordance in depressive symptoms and the following cognitive impairment and mortality: evidence from the china health and retirement longitudinal study [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/1595

Author names and title formatting were generated automatically from the congress system; please check them against the original poster before use.

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