# Association between bone mineral density and clinical parameters in bipolar disorder: a cross-sectional study

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- Page title: Association between bone mineral density and clinical parameters in bipolar disorder: a cross-sectional study | WCP 2026 Summary

> Low bone mineral density was common in young patients with bipolar disorder, and greater symptom severity was significantly associated with poorer bone status…

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This page is an AI-assisted Turkish summary of the study presented at the 26th World Congress of Psychiatry. The study belongs to the presenting authors; please refer to the original source when citing it.

EV0354

E-PosterMood and AnxietyCross-sectional study

# Association between bone mineral density and clinical parameters in bipolar disorder: a cross-sectional study

ASSOCIATION OF BONE MINERAL DENSITY WITH CLINICAL PARAMETERS IN BIPOLAR DISORDER: A CROSS-SECTIONAL STUDY

Presenter: Parth Kanchkar

Country: India

Low bone mineral density was common in young patients with bipolar disorder, and greater symptom severity was significantly associated with poorer bone status at different skeletal sites.

The aim was to determine the prevalence of low bone mineral density (BMD) and its association with clinical parameters in patients with bipolar disorder. In this cross-sectional study, 96 patients aged 18–45 years who had been diagnosed according to ICD-10 DCR criteria were assessed using purposive sampling at AIIMS Raipur, India (mean age 32.2 ± 8.2 years; 61.5% male, 38.5% female). BMD was measured by dual-energy X-ray absorptiometry (DEXA) at the femoral neck (FN), lumbar spine (LS), and total hip (TH), and osteoporosis was defined as a Z-score below -2 SD; clinical assessments used the Hamilton Depression Rating Scale (HAMD-17), Young Mania Rating Scale (YMRS), and Clinical Global Impression Scale (CGI); exclusion criteria included substance dependence, pregnancy, lactation, postmenopausal status, locomotor disability, malignancy, medical instability, and secondary osteoporosis. At the lumbar spine, 52% of participants had normal bone density, 27% had low bone mass, and 21% had osteoporosis; at the hip, 57% had normal bone density, 35% had low bone mass, and 8% had osteoporosis, with osteoporosis more frequent at the lumbar spine than at the hip. In the clinical correlation analyses, the CGI-S score for the most recent episode was significantly associated with lumbar spine measurements (p=0.049), while the CGI-S score for the previous episode (p=0.034), total HAMD score (p=0.042), and total YMRS score (p=0.046) were significantly associated with hip and femoral neck measurements. The authors reported that greater clinical severity was associated with poorer bone status across skeletal sites and that reduced BMD represents an underrecognized burden in young patients with bipolar disorder. The clinical implication is that early risk assessment and targeted bone health screening should be considered, particularly in resource-limited settings.

[View the original poster](https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/645)

How to cite this study

APA 7: Kanchkar, P., Kumar, A., Somani, A., Ghosh, A., & Shah, S. (2026, September 23-26). Association of bone mineral density with clinical parameters in bipolar disorder: a cross-sectional study [E-poster]. 26th WPA World Congress of Psychiatry (WCP 2026), Stockholm, Sweden. https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/645

Vancouver: Kanchkar P, Kumar A, Somani A, Ghosh A, Shah S. Association of bone mineral density with clinical parameters in bipolar disorder: a cross-sectional study [e-poster]. 26th WPA World Congress of Psychiatry (WCP 2026); 2026 Sep 23-26; Stockholm, Sweden. Available from: https://cslide.ctimeetingtech.com/wcp26/attendee/eposter/file/645

Author names and title formatting were generated automatically from the congress system; please check them against the original poster before use.

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